For PFK protein, the targeting pathway is CYTOPLASM ONLY.
For insulin protein, the targeting pathway is: ENDOPLASMIC RETICULUM TO THE GOLGI BODY TO THE OUTSIDE OF THE CELL.
There are basically two general targeting pathways for proteins in the eukaryotic cells. Proteins that function in the cytoplasm are released directly into the cytoplasm while other proteins are translated on ribosomes that are bound to rough endoplasmic reticulum.
Since Lithium has one valence electron that means it needs to lose it to form a stable structure. That means it's valence is equal to one. Oxygen has six atoms, in order to form a stable octet structure it needs to accept 2 electrons, therefore it's valence is 2.
Therefore two Lithium atoms bond with one oxygen atom to form Li2O
It can be found in tissues
Answer:
B. The father did not contribute a sex chromosome to his daughter due to nondisjunction of the sex chromosomes. The daughter is XO and her only X chromosome came from her mother, who was a carrier.
A.The mother's X chromosomes failed to separate during meiosis, and the daughter inherited two X chromosomes with the Lesch-Nyhan mutation. The father contributed no sex chromosomes.
Explanation:
As seen in the question above, a little girl was diagnosed with Lesch-Nyhan syndrome, which is an X-linked recessive condition caused by a mutation in the HPRT1 gene responsible for purine metabolism.
The little girl's parents do not have the syndrome, and no one in the little girl's paternal family presented this syndrome, however, we know that the maternal grandfather of the little girl's mother had the syndrome, which means that it was the mother's genetic material that contributed to the development of the syndrome in the little girl. This was because the little girl did not receive any X chromosomes from her father, but she inherited the two X chromosomes from her mother that coded for the Lesch-Nyhan mutation. This happened because the mother's X chromosome disjuction did not occur during meiosis I.
As shown above, the father did not contribute any sex chromosomes to his daughter, which means that the daughter is XO and her only X chromosome came from her mother, who was a carrier.
