somatic hypermutation occurs only in the <u>V or Variable</u> regions of rearranged heavy and light chains.
Somatic hypermutation occurs only in activated B cells, not T cells. This occurs in germinal establishments inside of lymph nodes and the spleen, where B cells are stimulated and T cells are present. Somatic hypermutation is a procedure in which point mutations pile up at rates 106-fold greater than the background mutation rates observed in other genes in the antibody V-regions of both the light and heavy chains.
Somatic hypermutation of immunoglobulin (Ig) genes is important in antibody-mediated immunity. SHM in B cells serves as the molecular foundation for antibody affinity maturation. In this way, SHM plays an important role in optimizing antibody-dependent immune responses.
For more information on Somatic hypermutation, visit :
brainly.com/question/16349768
#SPJ4
Answer:
Yes, there is a need to assure the client that this is a normal reaction.
Explanation:
In the given case, it is the duty of a nurse to assure the patient that swelling takes place while performing intradermal vaccination. As with the administration of disease-specific antigens, the injected area inflames that generally takes place due to the development of antibodies against the presented antigens.
Thus, both the patient and the nurse need to be calm in such a situation and should leave the swelling open so that it can get heal by itself. In case, if one applies ice packs or rubs the affected area, it can enhance the condition and may result in more issues.
Answer:
1 mint please
Explanation:
The diagram shows the life cycle of a chicken.
2
What does stage 3 show?
D they are easily contained charges so on and off is no problemo
C. It’s good to repeat experiments in case you miss something or something was off
