First law is Law of Conservation of Energy it states that enegy cant be made in a isolated system. The second law is Law of Thermodynamics it states that the entropy of any isolated system always increases.
<span>The globin chains of myoglobin and hemoglobin prevent the oxidation of Fe2 to Fe3 , which irreversibly binds oxygen. The cooperativity of oxygen binding in hemoglobin arises from electronic interactions between heme groups.</span>