A three banded isoenzyme pattern with a 1:2:1 intensity ratio indicates a <u>dimeric</u> protein.
- Isozyme is a multimeric forms of enzyme having similar specificity of the substrate but differences in kinetics and molecular weights of the enzymes.
- The banding patterns of isozyme observed from electrophoresis is related to the genetic conditions in which different combination of polypeptide chains exhibited under the mendelian principles.
- Hence with the intensity of 1:2:1 ratio, three banded phenotypes are formed having two homomeric and one heteromeric form from the dimeric protein in both multiple alleles at single loci and multiple /single allele at multiple loci.
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A lion, coyote, and others like hawks and eagles
When alzheimer disease sets in early and impacts those under age 60, the final phase of the disease or death typically occurs around 3 to 5 years after the first signs of the disease appear. Alzheimer's disease is the most common type of dementia, which is represents the memory loss and other cognitive abilities serious enough to interfere with normal life. Alzheimer accounts for about 60 to 80 percent of dementia cases.
