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romanna [79]
3 years ago
8

Which of the following contributes to the development of type 1 DM (diabetes mellitus)?

Health
1 answer:
Eddi Din [679]3 years ago
5 0

Autoantibodies that contribute to the destruction of beta cells contributes to the development of type I diabetes mellitus (DM)

Explanation:

The autoantibodies produced in the cells of the islet of Langerhans in the pancreas are the main contributors of type I diabetes mellitus, which is an autoimmune-mediated disease.

DM type I is caused due to inhibition of insulin secretion by the beta cells of the pancreas. The autoantibodies are produced due to the presence of autoantigens like GAD65 which causes autoimmune pathogenesis of the pancreatic beta cells.

Along with these autoantibodies, the T-cell receptors act as mediators in the destruction of beta cells which finally results in DM.

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Answer:

Option D

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Explanation:

The toes are made up of fourteen bones. Here is a breakdown below:

The big toe is made up of two major bones. These are the distal and the proximal phalanges (<em>singular - is called phalanx)</em>

The other four toes are made up of three different phalanges.

This gives a total of 14 bones <em>i.e  (4 X 3) + 2 = 14</em> which make up the toes that hold up the ballet dancer standing on pointe.

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In the duration section, you write down how long you did the activity. For example, you write down, "15:00" min for yoga and "30:00" min for basketball.

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