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irakobra [83]
2 years ago
9

A gene that has two alleles, A and a, is located on the same chromosome as a second gene that also has two alleles, B and b. Sup

pose a diploid individual has alleles AB on one copy of this chromosome and alleles ab on the other copy of this chromosome. For this individual, select the pair of recombinant genotypes that could result if crossing over occurs between these two chromosomes.1. AB and aB
2. Ab and ab
3. Ab and aB
4. AB and ab
Biology
1 answer:
o-na [289]2 years ago
7 0

Answer:

Option C or 3, i.e Ab and aB is correct

Explanation:

First copy of allele is AB

Second copy of allele is ab

The allele pair AB will segregate into genes A and B

The allele pair ab will segregate into genes a and b

The recombinant genotype will consist of one gene from each allele pair

Thus, if first allele pair give A gene the second allele pair will given b gene, so the genotype would be Ab

Likewise, if if first allele pair give B gene the second allele pair will given a gene, so the genotype would be aB

Option C or 3, i.e Ab and aB is correct

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1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).

2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).

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<u>Normal hemoglobin protein in a RBC</u>

DNA                 CTG ACT CCT GAG GAG AAG TCT

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<u>Sickle cell hemoglobin protein in a RBC</u>

DNA                 CTG ACT CCT <em>GTG</em> GAG AAG TCT

Amino acids     Leu  Thr   Pro   <em>Val</em>   Glu   Lys   Ser

When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.

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The best answer would be:
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