1. Cells are the fundamental unit of structure and function in living things.
2. All living things are composed of cells.
3. All cells come from preexisting cells.
Regular exercise helps make us more alert and energetic, by releasing endorphins which is a chemical that improves our mood.
I believe "reasonable" would be the word you are looking for there.
The spleen plays an important role in the immune system, therefore when the spleen is no longer present the immune system weakens and can cause the affected to become more susceptible to illness/infection. Furthermore, the affects individual will have a harder time fighting the illness/infection than someone with a full immune system.