A eukaryotic gene contains 14 exons. Most of the transcripts from this gene contain all 14 exons, but some contain only 11 exons
. Only the 14-exo mRNA encodes a protein that changes its cellular localization in response to phosphorylation. Which mechanisms for producing complexity are exemplified by this gene? Check All That Apply A. DNA-level comblnatorial amplification B. pseudogene formation C. gene duplication and divergence D. alternative splicing E. posttranslational modification
D. Alternative splicing is the mechanism that produce complexity in the genes by splicing some of the protein coding part (exons) of a genes
Explanation:
There are certain splicing enhancers sites present in Exons which facilitiates the binding of RNA binding protein specifically SR protein family rich in Serine and Arginine residues. This SR protein will help in splicing of exons.
The significance of this type of mechanism is the ability of a cell to produce an isoform of protein which have retain their function.
This mechanism also help is diversity or in short in evolution.
