Prior to therapy, a high PpIX fluorescence was observed in three patients; however, after iPDT, this fluorescence was entirely photobleached. These patients' viable tumor sections had high PpIX concentrations (mean PpIX uptake per tumor: 1.4-3.0 M).
<h3>Briefing:</h3>
However, no or just minimal PpIX uptake (0-0.6 M) could be seen in the remaining two cases. Strong PpIX uptake patients demonstrated therapeutic response and long-term clinical stabilization (no progression at 29, 30, and 36 months); the remaining two patients experienced early treatment failure (death after 3 and 9 months).
<h3>Describe fluorescence:</h3>
Two steps make up the chemical process of fluorescence first, a chemical fluorophore such a protein or carotenoid absorbs shorter-wavelength light (excitation), and then some of the absorbed energy is released as longer-wavelength light (emission).
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Answer:
A mutation is a change that occurs in our DNA sequence, either due to mistakes when the DNA is copied or as the result of environmental factors such as UV light and cigarette smoke.
Because it depends on the amount of humidity and perspiration produced in that area
Im confused about the question can you explain
