Question

Previous genetic linkage crosses have determined that recombination frequencies are 6% for genes A and B, 4% for genes B and C, 10% for genes C and D, and 11% for genes D and E. The sum of these frequencies between genes A and E is 31%. Why does the recombination distance between these genes as determined by adding the intervals between adjacent linked genes differ from the distance determined by the test cross?

Answer 1

Answer:

Because as distance between genes increase, the probability of one recombination grows, but the probability of two recombinations occuring also increases

Explanation:

If we only score the outcome as yes or no to recombination between two genes, then one recombination is a yes, but two is a no and three is a yes again (and so on).