Muscle, hair color, height are the 3 most common physical traits affected by the environment.
Bacteria! Bacteria! Bacteria! :)
I looked up your question just now and found this sight that has plenty of answers in it. https://www.britannica.com/place/Appalachian-Mountains
Hope this helps.
Answer:
Muscles can also receive messages from the brain when the body temperature decreases. They respond by shivering. Shivering causes the muscles to contract and relax quickly. This process generates heat.
It is Nucleic Acids, they consist of long chains of units like the proteins, but still both are different.