Answer:
A) A transgene integrated into a heterochromatic region of the genome.
Explanation:
This is most likely the reason why the transgene is not expressed in the fifth cell line. It is likely that the transgene was integrated into a heterochromatic region of the genome. Heterochromatin consists of genetically inactive satellite sequences, and many of these are repressed to various extents. Moreover, because this is a tightly packed form of DNA or condensed DNA, it is inaccesible to polymerases and thus not transcribed.
The goal is to find out how often effective antimicrobial therapy is delayed after the start of persistent or recurrent hypotension in septic shock and how this affects mortality.
Design: A cohort research that was conducted in retrospect between July 1989 and June 2004.
Setting: Ten hospitals (four academic, six community) and fourteen critical care units (four medical, four surgical, and six combined medical/surgical) located in Canada and the United States.
Patients: The 2,731 adult patients with septic shock listed in their medical records.
Measurements and key findings: Survival to hospital discharge served as the primary outcome indicator. A survival percentage of 79.9% was found when an antibiotic efficacious for isolated or suspected infections was administered within the first hour of verified hypotension. Over the following 6 hours, each hour of antibiotic delivery delay was linked to an average 7.6% decline in survival. When compared to obtaining treatment within the first hour after the beginning of persistent or recurrent hypotension, the in-hospital mortality rate was considerably higher by the second hour (odds ratio 1.67; 95% confidence range, 1.12-2.48). The single best predictor of outcome in multivariate analysis (which included Acute Physiology and Chronic Health Evaluation II score and treatment factors) was time to the start of effective antimicrobial therapy. It took 6 hours on average to start effective antimicrobial therapy (25-75th percentile, 2.0-15.0 hrs).
Conclusions: In adult patients with septic shock, effective antibiotic therapy during the first hour of confirmed hypotension was related with enhanced survival to hospital discharge. Only 50% of patients with septic shock got efficient antimicrobial therapy within 6 hours of being diagnosed with proven hypotension, despite a steady rise in fatality rate with increasing delays.
<h3>What is
septic shock?</h3>
Septic shock is a potentially fatal illness that develops after an infection when your blood pressure drops to an unsafely low level. The infection might be brought on by any kind of bacterium.
To learn more about septic shock with the help of given link:
brainly.com/question/4235870
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61% of emerging diseases is caused by zoonotic pathogens
Explanation:
Out of total emerging diseases zoonotic contributes 61%, that are originated from wildlife. The rate is increasing due to growth of human population, its mobility, frivolous, cultural and their socioeconomic purposes. Air is the major source for spread of infectious diseases. Zoonoses are generally caused by bacteria, viruses and pathogens that are blowout between animals and human beings. Modern zoonoses are Ebola virus and salmonella. One of such direct zoonoses is rabies, that is transformed directly from animal to human.
Answer:
True.
Explanation:
There are four phases which occur during karyokinesis, these are -
- Prophase
- Metaphase
- Anaphase
- Telophase
Telophase is the last phase of karyokinesis. The main events that occur during telophase are-
- Uncoiling of chromosome occurs
- Chromatin is formed
- Spindle breaks down
- Nuclear membrane or nuclear envelope if reformed
Thus it is clear that the events that are mentioned in the question denote truly about the Telophase.
