Pressure, temperature, and idk the last one:/
The cell would fall apart it has no walls to hold it together
Isotopes are variants of a particular chemical element which differ in neutron number, although all isotopes of a given element have the same number of protons in each atom. The term isotope is formed from the Greek roots isos and topos, meaning "the same place"; thus, the meaning behind the name is that different isotopes of a single element occupy the same position on the periodic table.
B looks like the best to me