Answer: Mutations are permanent alteration in the nucleotide sequence of a DNA. Mutations result in the production of nonfunctional or malfunctioning proteins.
Explanation: Mutations are errors that normally occur during replication as new nucleotides are added to the growing polynucleotide chain. The result is a mutated DNA molecule, and this leads to the production of an mRNA molecule with an altered nucleotide sequence during transcription and consequently, the production of aaprotein nonfunctional protein with an altered amino acid sequence.
Point mutations can cause serious changes to an organism if they change the way a protein works. A mutation in DNA alters the mRNA, which in turn can alter the amino acid chain. A base substitution may have three different effects on an organism's protein.
