Acute leukemia happens when most of the abnormal blood cells don't mature and can't carry out normal functions. It can get bad very fast. Chronic leukemia happens when there are some immature cells, but others are normal and can work the way they should. It gets bad more slowly than acute forms do
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
It it possible and is very lucky and should clear the area as it could go of and blow at any moment.
Explanation:
The given article discusses about the evaluation of the Chest Pain Dashboard.
<h3>What is the result of the article?</h3>
A difference-in-difference analysis suggests that the ED with the Dashboard implementation resulted in a significant increase in HIE use compared to EDs without. This finding was supported by qualitative interviews. While these results are encouraging, we also identified areas for improvement. FHIR-based solutions may offer promising approaches to encourage greater accessibility and use of HIE data.
<h3>What is Chest Pain?</h3>
One of the most frequent causes for emergency room visits is chest pain (ER). Each person experiences chest discomfort differently. It differs as well in:
It could seem like a mild ache or a severe, searing pain. It could indicate a major heart condition or be the result of a less serious, common reason.
<h3>What causes Chest Pain?</h3>
Your initial assumption while experiencing chest pain can be that you are having a heart attack. Although chest discomfort is a recognized indicator of a heart attack, there are numerous other less dangerous diseases that can also cause it.
Only 5.5% of all ER visits for chest discomfort, according to one study, result in the identification of a significant cardiac condition.
Learn more about chest pain with the help of the given link:
brainly.com/question/2416451
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