Answer:
c. cerebrospinal fluid
Explanation:
Cerebrospinal fluid
This fluid is a colorless , clear body fluid , that is present in the brain and the spinal cord .
Some specialized ependymal cells produces this fluid .
Around 125 mL of Cerebrospinal fluid is produced at one time , and around 500mL is produced daily .
The Cerebrospinal fluid is nearly 99% water which means it contain highest volume of fluid .
Answer:
Explanation:
People can be bias, when political terms come into place, sometimes gender/body figure...
COPD, emphysema, bronchitis , and asthma. Chronic obstructive pulmonary disease (COPD), which incorporates chronic bronchitis.
<h3>What about chronic obstructive pulmonary disease?</h3>
- COPD symptoms include persistent coughing or wheezing.
- Excessive sputum or phlegm.
- Respiration difficulty.
- The signs and symptoms include wheezing, expulsion mucus (sputum), and trouble breathing.
- It's frequently brought on by prolonged exposure to irritant gases or particulates, most often from cigarette smoke.
- Heart disease, carcinoma , and a variety of other diseases are more likely to occur in people with COPD.
- In around 9 out of each 10 cases, smoking is regarded to be the first cause of COPD.
- The lining of the lungs and airways can get damaged by the toxic compounds in smoke.
- Quitting smoking can help stop the deterioration of COPD.
- Short-acting bronchodilator inhalers are the initial line of therapy for the bulk of COPD patients.
- Breathing is formed easier by bronchodilators, which relax and expand the airways.
- Short-acting bronchodilator inhalers are available in two varieties: beta-2 agonist inhalers, like salbutamol and terbutaline.
- For those with chronic obstructive pulmonary disease (COPD) who have (or are in danger for) hypercapnia, an excessive amount of oxygen can be harmful.
- Patients with hypercapnia are frequently over oxygenated, despite established standards and acknowledged danger.
Learn more about chronic obstructive pulmonary disease here:
brainly.com/question/11151912
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Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
The answer to this question is rather “true” ! :)