Following a flood, migration from neighboring populations alters genotypic frequencies of a population of river-bottom midges. A
ssuming that the conditions for Hardy–Weinberg subsequently are met, how many generations of random mating are required to restore the genotypic frequencies to Hardy–Weinberg equilibrium?(A) Between 3 and 10(B) Between 11 and 20(C) 2(D) 1(E) More than 20
Explanation: Hardy-Weinberg (H-W) principle assumes the following;
1. Random mating
2. No migration
3. No selection
4. No mutation
5. Large population
When genotype frequencies in a population deviate from H-W principle, it takes only one (1) generation of random mating to H-W equilibrium if the above assumptions hold, that the frequencies in males and females are equal and that the locus is autosomal.
In the case of different allele frequencies between the sexes, it will take two (2) generations of random mating to H-W equilibrium.
Also, it will take multiple generations to attain equilibrium for sex-linked loci because one sex has two copies of the gene and the other sex has only one.
Contact inhibition is a process of arresting cell growth when cells come in contact with each other. As a result, normal cells stop proliferating when they form a monolayer in a culture dish. Contact inhibition is a powerful anticancer mechanism that is lost in cancer cells (16).