The great awakening was about making people individualists when it came to religion. Moving away from institutionalized religion and into the realm of self-reflection and religion being a personal thing. Since the religion was usually tied to the country, making it a personal thing could have implications that governing of a state should be a personal thing, that is that people should not have a monarchy and rather a republic.
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https://www.battlefields.org/learn/articles/naval-actions-civil-war
There are hardly any
It's mostly side effects such as mild fevers and stuff, but vaccines are a must
