Question

Carboxypeptidases can be used to determine the entire sequence of short peptides (<50 amino acid residues) and it starts by reacting with the C-terminal amino acid.
a. True
b. False

Answer 1

Answer:

A. True

Explanation:

Carboxypeptidases are enzymes which function in the digestion of short peptides known as oligopeptides in the small intestine. Oligopeptides contain between 10 to 50 amino acid residues.

The two carboxypeptidases A and B involved in the digestion of proteins in the small intestine are secreted by the exocrine glands of the pancreas.They are both zinc-containing enzymes which remove successive carboxyl-terminal  (C-terminal) residues from oligopeptides until free amino acids are obtained.

Since they function in this way, they can be used to determine the entire sequence of short peptides or oligopeptides.