The wastes would build up in your blood, and can cause serious damage. You can also have serious infections and pain if your kidney is not functioning properly.
The endoplasmic reticulum, or ER, and Golgi apparatus, prepare molecules, including proteins, hormones and lipids, and package them in vesicles for transport. Rough ER is studded with ribosomes that synthesize proteins, while the smooth ER manufactures lipids.