The chloromethylated polystyrene resin used for Merrifield solid-phase peptide synthesis is prepared by treatment of polystyrene
with chloromethyl methyl ether and a Lewis acid catalyst. The reaction involves the following steps: Reaction of the ether with the Lewis acid to form cation 1; Electrophilic aromatic substitution to form resonance stabilized cation 2; Deprotonation yields aromatic ether 3; Protonation to form protonated ether 4; Displacement by chloride ion to form the final product. Write out the mechanism on a separate sheet of paper and then draw the structure of the resonance contributors of the resonance stabilized cation 2.
1 answer:
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Answer : The correct option is, (C) 1.1
Solution : Given,
Initial moles of = 1.0 mole
Initial volume of solution = 1.0 L
First we have to calculate the concentration .
The given equilibrium reaction is,
Initially c 0
At equilibrium
The expression of will be,
where,
= degree of dissociation = 40 % = 0.4
Now put all the given values in the above expression, we get:
Therefore, the value of equilibrium constant for this reaction is, 1.1