This statement, "Practicing and specific training can improve components of skill related fitness limited by heredity, is True. Even if you have hereditary disadvantages, you can work hard to compensate for them.
A person with sickle cell anemia will have:
Fatigue and Anemia are the most common to occur if you have SCA.
Dactylitis (swelling and inflammation of the hands and/or feet) and Arthritis is also common most likely garenteed to happen.
Splenic Sequestration (sudden pooling of blood in the spleen) and Liver Congestion is fatal and needs to be treated right away.
I hope this helps you :)