Local anesthetics inhibit nerve conduction in a reversible manner without altering the nerve. The inhibition appears rapidly and for a longer or shorter duration depending on the products and the concentrations used. The extent of the territory rendered insensitive to pain depends on the modes of administration of the local anesthetic, either at the level of the nerve endings, or at the level of a nervous trunk, for example.
They act at the level of the neuronal membrane by interfering with the process of excitation and conduction. The anesthetic crosses the axon membrane, rich in lipids, in the form of base before taking up a cationic form on the internal face of the neuron where the pH is more acidic.
At this level, there is a blockage of nerve conduction by decreasing the membrane permeability to sodium ions that occurs during the depolarization phase. As the progression of the anesthetic action along the nerve increases, the threshold of excitability increases and the conduction time increases. This is completely blocked from a certain concentration of local anesthetic.
The nerve fibers are unequally sensitive to the action of local anesthetics: they disappear in order: the painful, thermal, tactile sensations.
Answer:
A and C are both long term challenges, I'm pretty sure it's A.
Explanation:
Personal experience, I have arthritis and it's a long term challenge.
Answer:
ask more questions to open up and definitely confront the problem to her so you guys can work it out because if you don't and you both keep holding back it's not finna help nun so just go to her talk to her get out of you comfort zone. make the first moves yk don't hold back communication is key.
Always think better. For example think of it this way, you may not be alive tomorrow, appreciate what you have.
Also you can just do what you want, once you die, you cant do the things you wanted.
I’m pretty sure this is true, i don’t play basketball though
