A well, 2-year-old girl presents to the clinic with symptoms of a viral illness. Her parents report she has had bouts of vomitin
g and diarrhea over the last 24 hours. This morning they could barely wake her from her crib and she was very weak. Laboratory tests show low blood glucose (hypoglycemia) and elevated liver enzymes. There are no ketones present in her urine. The child is hospitalized and glucose is administered by I.V. Additional laboratory analysis showed elevated medium-chain fatty acyl carnitines in blood and 6–8 carbon dicarboxylic acids in the urine. Which of the following abnormalities is the most likely diagnosis for this child?
Medium-chain coenzyme A dehydrogenase is a very important enzyme in the process of fatty acid oxidation. This process is used to provide energy when the glucose reserves have been depleted, however, this process is impossible in the absence of coenzyme A dehydrogenase.
It means when 2 bones grow closer to each other and causes pain. This procedure fuses, or “welds,” together the two bones that make up your aching joint. It causes the bones to become one solid bone, and it can lessen your pain.
