<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
Answer:
Option (c).
Explanation:
Transcription may be defined as the process of formation of RNA molecule from the template DNA with the help of enzymes and transcription factors. The transcription occurs in 5' to 3' direction.
Post trancriptional modification occurs in the RNA molecule that plays an important role in transcription as well as translation. The introns are removed from the RNA transcript and exons joined together is known as splicing. The alternative splicing occurs in which different protein isoforms are formed by the single exons.
Thus, the correct answer is option (c).
Cellular respiration is the process that cells use to break down food to use as an energy. Aerobic cellular respiration uses oxygen and yields many more ATP molecules than anaerobic cellular respiration, which does not use oxygen and yields only two ATP molecules.
