Question

this classification of drug typically changes the brain's chemistry and reduces its ability to create its own endorphins

Answer 1

Regular use of opioids may reduce the brain's production of endorphins.

Answer 2

This classification of drug typically changes the brain's chemistry and  

reduces its ability to create its own endorphins.

options:

Stimulants

Depressants

Hallucinogens

Narcotics

I believe the answer is Hallucinogens  but Hallucinogens  can be considered to be Narcotics so its out of those two.