Methanogens, halophiles, thermophiles
Answer:
In p53 pathways, 3 proteins which are mutate and cause cancer that proteins are:
1.BRCA2
2. p53 in Rb genes binds with deoxyribonucleic acid that stimulates another gene to produce a protein known as p21 that interacts with cdk2. When p21 is combined with cdk2 cell will not pass through to the next stage of cell division. This is Li-Fraumeni syndrome (when p53 causes cancer from parents to offspring)
3.BRCA1
The parent that transmits mutation in one of these genes has a 50% chance of inheriting the mutation. The effects of mutations in BRCA2 and BRCA1 are seen when the person's second copy of the gene is normal.
Answer:
Enzyme inhibitors may alter the elimination rate of a particular drug or inhibit detoxication pathways
Explanation:
An enzyme inhibitor is a chemical compound capable of binding to an enzyme in order to reduce its activity. An enzyme inhibitor may bind to an active site and thus decreases the rate of reaction (direct inhibition). Enzyme inhibitors may act 1-to Inhibit detoxification enzymes and 2-reduce the elimination rate of enzyme drugs, thereby having dose-dependent toxicity effects. For example, many medicines are based on the inhibition of Cytochromes P450 (CYPs) proteins, which are a superfamily of enzymes required for drug metabolism.
Hi
Below are five major steps of DNA or gene cloning:
1: You chose the gene or specific piece of DNA you need to clone and cut the gene with restriction enzymes from the source organism.
2: You need to choose a vector for the process of cloning and you will cut the vector with same restriction enzymes through which you have cut your target DNA sequence to be inserted into the vector.
3: You place the target gene into the vector and join or seal the gene with vector by using an enzyme called DNA ligase.
4: You introduce the vector with your target gene into a suitable host organism such as yeast or bacteria through the process of Transformation. In this process host organism takes up the vector containing your target gene and starts replicating the target DNA along with their own DNA and thus creating millions of copies of target gene .
5: In the last step, the DNA or target gene is isolated from host organism and purified and is ready to be used since its quantity has been enormously increased through the process of cloning.
The cloning is also called as recombinant DNA technology and is the main process that is being used in the production of insulin for diabetes patients. You can see below image for better understanding.
Hope it help!
The reason both of these are valid scientific hypotheses is because A) scientists with different educational backgrounds may put forth different hypotheses to explain the same data.
This approach in science is vital in making progress and has helped to explain many phenomena in the past. When scientists explain data using different approaches, they come to a more comprehensive conclusion.
