Answer:
HeLa cells, like many tumours, have error-filled genomes, with one or more copies of many chromosomes: a normal cell contains 46 chromosomes whereas HeLa cells contain 76 to 80 (ref) total chromosomes, some of which are heavily mutated (22-25), per cell.
Explanation:
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The genetic change causes alterations in only one or a few nucleotide bases in known as mutation.
A mutation is a change in a brief section of a genome's nucleotide sequence. Another frequently replaces one nucleotide in point mutations; other changes involve the insertion or deletion of one or more nucleotides.
Errors in DNA replication or the harmful effects of mutagens, such as chemicals and radiation, which react with DNA and alter the architecture of individual nucleotides, are the leading causes of mutations.
DNA repair enzymes are present in all cells and work to reduce the frequency of mutations. These enzymes reduce genetic information loss, double-strand break formation, and DNA crosslinking by repairing DNA damage.
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During interphase, the cell grows and builds the nutrients required for the stage called Mitosis that prepares it for cell division and manipulate the dna