Question

A certain geneticist is interested in the proportion of males and females in the population who have a minor blood disorder. In a random sample of 1000 males, 250 are found to be afflicted, whereas 275 of 1000 females tested appear to have the disorder. Compute a 95% confidence interval for the difference between the proportions of males and females who have the blood disorder.

Answer 1

Answer:

95% confidence interval for the difference between the proportions of males and females who have the blood disorder is [-0.064 , 0.014].

Step-by-step explanation:

We are given that a certain geneticist is interested in the proportion of males and females in the population who have a minor blood disorder.

A random sample of 1000 males, 250 are found to be afflicted, whereas 275 of 1000 females tested appear to have the disorder.

Firstly, the pivotal quantity for 95% confidence interval for the difference between population proportion is given by;

                        P.Q. = $\frac{(\hat p_1-\hat p_2)-(p_1-p_2)}{\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$  ~ N(0,1)

where, $\hat p_1$ = sample proportion of males having blood disorder= $\frac{250}{1000}$ = 0.25

$\hat p_2$ = sample proportion of females having blood disorder = $\frac{275}{1000}$ = 0.275

$n_1$ = sample of males = 1000

$n_2$ = sample of females = 1000

$p_1$ = population proportion of males having blood disorder

$p_2$ = population proportion of females having blood disorder

Here for constructing 95% confidence interval we have used Two-sample z proportion statistics.

So, 95% confidence interval for the difference between the population proportions, ($p_1-p_2$) is ;

P(-1.96 < N(0,1) < 1.96) = 0.95  {As the critical value of z at 2.5% level

                                             of significance are -1.96 & 1.96}  

P(-1.96 < $\frac{(\hat p_1-\hat p_2)-(p_1-p_2)}{\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$ < 1.96) = 0.95

P( $-1.96 \times {\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$ < ${(\hat p_1-\hat p_2)-(p_1-p_2)}$ < $1.96 \times {\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$ ) = 0.95

P( $(\hat p_1-\hat p_2)-1.96 \times {\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$ < ($p_1-p_2$) < $(\hat p_1-\hat p_2)+1.96 \times {\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$ ) = 0.95

95% confidence interval for ($p_1-p_2$) =

[$(\hat p_1-\hat p_2)-1.96 \times {\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$, $(\hat p_1-\hat p_2)+1.96 \times {\sqrt{\frac{\hat p_1(1-\hat p_1)}{n_1}+ \frac{\hat p_2(1-\hat p_2)}{n_2}} }$]

= [ $(0.25-0.275)-1.96 \times {\sqrt{\frac{0.25(1-0.25)}{1000}+ \frac{0.275(1-0.275)}{1000}} }$, $(0.25-0.275)+1.96 \times {\sqrt{\frac{0.25(1-0.25)}{1000}+ \frac{0.275(1-0.275)}{1000}} }$ ]

 = [-0.064 , 0.014]

Therefore, 95% confidence interval for the difference between the proportions of males and females who have the blood disorder is [-0.064 , 0.014].