The part of the nephron that In which part of the nephron are sodium and chloride ions are actively reabsorbed is the Henle's loop. It <span>is the portion of a </span>nephron<span> that leads from the </span>proximal convoluted tubule<span> to the </span>distal convoluted tubule<span>.</span> It's main function is to make a concentration gradient in the medulla of the kidney.