A scientist notices that when she adds a small, water-soluble molecule to a dish of cells, the cells turn off transcription of a

Question

2 years ago

13

A scientist notices that when she adds a small, water-soluble molecule to a dish of cells, the cells turn off transcription of a

gene. She hypothesizes that the ligand she added binds to a(n) ______ receptor. Intracellular Hormone Enzyme-linked Gated ion channel-linked

Biology

1 answer:

Lelechka [254] · Answer 1 · 2022-08-02T11:07:59+03:00

Answer:

Enzyme-linked

Explanation:

The cell surface receptors that have intracellular domains associated with enzymes are called enzyme-linked receptors. The added molecule was water-soluble and cannot pass through the membrane to bind to intracellular receptors. Binding of the added molecule to the enzyme-linked receptor led to the activation of associated enzymes to generate the response (down-regulation of expression of the target gene).

Examples of enzyme-linked receptors include tyrosine kinase receptors. Binding of the signaling molecule to these receptors triggers phosphorylation of the intracellular domain which in turn transmits the signal to the cytoplasmic messenger.