Question: Describe how a single amino acid substitution causes hemoglobin molecules to stick together. Use what you know about the structure of Hb and HbS, the properties of glutamic acid and valine, and how hydrophobicity causes molecules to behave in water.
Answer:
A Single amino acid must be polar to attract, just like water.
Explanation:
Sickle cell is an genetic illness and it is began by a alteration that arises in the beta sub units of the haemoglobin. Haemoglobin is a tetrameric protein made up of 2 alpha sub units and 2 beta sub units and it is the important part of the blood accountable for oxygen passage. Sickle cell is a illness that consequences from a replacement of a polar amino acid identified as glutamate with a non polar one valine at site six of the beta polypeptide component of haemoglobin. The replacement occurs as a consequence of a alteration in one of the bases in the beta-globin gene from adenine to thymine . As a outcome of this change, the beta polypeptide chains convert sticky in low oxygen circumstances since the valine sticks out of the chain and interrelates with neighboring non-polar amino acids.
Answer:
Aa
Explanation:
In Punnett Square, you are bringing the letters on the top to the numbered squares, if that makes sense. It is to predict the genotype of offspring.
So square 1, on the left is A, and on the top is A, so it would be AA.
For square 2, on the left is a, and on the top is A, so it would be Aa.
For square 3, on the left is A, and on the top is A, so it is AA.
Square 4, your question, has a on the left, and A on the top, so it is Aa.
Hope it makes sense. You should probably watch a Punnett Square tutorial online or something for a full and more general explanation.
Answer:
1. Alzheimer's disease is when you begin to forget things and have memory loss.
2. It is inherited in an autosomal dominant pattern and if one of your parents has Alzheimer's you or your siblings could get it.
3. Single gene inheritance
Explanation:
The correct answer is d. 8p+; 9n; 10e−
Oxygen exists in three isotopes ¹⁶O, ¹⁷O and ¹⁸O. The atomic number of oxygen is 8. It means its nuclei has 8 protons. The given is oxide⁻² anion. This means it has gained 2 electrons. Thus, oxide anion have 8 protons and 10 (8+2) electrons. The number of neutrons depends on the isotope, in this question mass number is given¹⁷O. The mass number is the sum of the protons and neutrons in the nucleus. Hence, number of neutrons oxide anion will be 17-8 = 9 neutrons.
