MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
The cell cycle ensures the duplication of the genome and its distribution in daughter cells by passing through a coordinated and regulated sequence of events.
A series of checkpoints guarantee the orderly progression of the phases of cell division and the correct distribution of the duplicated genetic material in the daughter cells.
The checkpoints during mitosis are:
- At the end of stage G1 and before S.
- Before anaphase in mitosis.
- DNA damage checkpoints in G1, S or G2.
The checkpoint before anaphase in mitosis guarantees the separation of chromosomes, and operates by activating the Mad2 protein that prevents the degradation of segurin, until the conditions are appropriate.
That is, the Mad2 protein prevents the segregation of sister chromatids until they have all bound to the spindle.
Therefore, we can conclude that MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
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Science and technology could help cure diseases, they also could help created new cures for other things. Technology could be added into science because when they are making prosthetic recourse using those two resources.
Based on the marginal propensity to save, MPS , the national income will increase by a maximum of $20 billion.
<h3>What is marginal propensity to save?</h3>
Marginal propensity to save (MPS) is a measure of how savings will change, given a change in income.
Marginal propensity to save is related to marginal propensity to consume, MPC by the formula:
Grom the given value of MPS,
MPC = 1 - 0.25
Therefore, MPC = 0.75
Also, the formula for calculating marginal propensity to consume is given as:
- Marginal propensity, MPC = ΔC/ΔY
Where:
- ΔC is a change in consumption
- ΔY is a change in income
ΔY = ΔC/MPC
ΔY = $15 billion/0.75
ΔY = $20 billion
Therefore, the national income will increase by a maximum of $20 billion.
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