I just woke him crying and he said I can’t he just got out here and I don’t know why I was just talking abt it and he was just trying so hard to sleep in his
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Answer:
The correct insulin pathway is described as under:
2. Binding of insulin to the alpha subunit of the insulin receptor
8. Activation of insulin receptor tyrosine kinase
3. Phosphorylation of IRS proteins
6. Phosphorylation of phosphinositide 3-kinase (PI-3K)
4. Conversion of PIP2 to PIP3
7. Activation of PIP3-dependent protein kinase B (PDK1)
5. Glut4 receptors transported to the cell membrane
Explanation:
The insulin signaling pathway is described as under:
RTK (receptor tyrosine kinases) which is a receptor for insulin is an extracellular receptor but in contrast to other cell surface receptors it is catalytic in nature. In the absence of insulin (ligand), it is monomeric but as soon as it gets activated (activation occurs upon ligand binding), it undergo dimerization. It leads to auto-phosphorylation in it's tyrosine residue which subsequently leads to phosphorylation of tyrosine residue of other receptors. Such hyper-phosphorylated receptor have high affinity with enzyme/molecule like IRS protein which have SH2 domain . IRS down stream activates phosphinositide 3-kinase (PI-3K). This enzyme converts component of animal cell membrane PIP2 into PIP3. PIP3 also remains membrane bound but it has the potential to phosphorylate another enzyme named as PIP3-dependent protein kinase B (PDK1). Further, PDK1 leads to the activation of Akt or PK-B. Akt is a serine-threonine kinase which ultimately leads to the recruitment of Glut4 receptors on cell membrane for uptake of more and more glucose into the cell.
Note: Apart from this Akt also phosphorylates another protein named as FOXO which ultimately causes cell growth, Akt can also phosphorylate BAD protein so as to restrict cell apoptosis or we can say it leads to cell survival, Akt also leads to translation in a cell with the help of mTOR raptor etc.
Answer:
(D) Strenuous exercise has caused her body to be in oxygen debt, and she is breathing hard while lactate is transported to the liver. This is a result of anaerobic respiration.
Explanation:
As Frida was exercising, her muscle cells were undergoing a frantic pace of metabolism (contraction and relaxation), where oxygen supply did not supply the required effort, thus causing muscle fatigue and heavy breathing.
Physical activity is synonymous with moving muscles. The more muscle fibers strive to accomplish a task, the more they consume the oxygen brought into the bloodstream. When this occurs, the body begins to breathe hard as lactate is transported to the liver.
This forces the lungs to work at a fast pace, as they are responsible for oxygenation. The heart also speeds up because it needs to pump blood more vigorously. This is why during exercise the heart rate and breathing rate increase and we breathe heavily.
Answer:
a solution of each sodium salt at the same concentration
Explanation:
If a scientist wishes to study the electrical potential that develops between ice and the sodium salts solution of the ions (F-, Cl-, Br-, or I-) in order to determine which ion produced the greatest electrical potential; he must compare the electrical potential that develops between ice and a solution of each sodium salt at the same concentration.
This means that conclusions can not be reached unless the sodium salt of each ion at the same concentration is compared so as to ensure consistence in the results of the study.
