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Cyclins and cyclin-dependent kinases are responsible for the progress of the cell through the various checkpoints.
The answer is pronuclei. A pronuclei is the state of the
nucleus of either the sperm or the ovum after the sperm has entered the ovum
but the two nuclei have not yet fused. When the sperm enters the ovum, the membrane
of the sperm pronuclei dissolves hence leaving no barrier for the two genetic
materials to combine.
