that they are not soluble with water
If a somatic human cell is about to divide, then it has 92 chromatids. this is because there are 23 pairs of homologues chromosomes in a cell, one is given by both parents. when a cell divides my mitosis, the pairs separate into 46 chromatids, each one that is replicated which gives you 92 chromatids.
Immunosuppressants, by it's name itself, suppresses or inhibits the immune system for functioning in a certain amount of time. It is administered usually during transplant surgeries, so that the new cells of the organ does not get killed by the recipient's immune system.