Garrod hypothesized that "inborn errors of metabolism" such as alkaptonuria occur because...genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes.
Explanation:
Archibald Garrod researched on alkaptonuria and proposed the ‘one gene-one enzyme’ hypothesis. This led to the finding that alkaptonuria is caused due to an inherited or “inborn error of metabolism”.
This hypothesis stated that each gene codes and responsible for a single specific enzyme which facilitates a particular step in the metabolic processes.
According to Garrod, a mutation of a particular gene leads to specific error or defect leading to a lack of a particular enzyme that takes part in the biochemical metabolic pathways. This disrupts the metabolic pathway at the specific enzymatic action point.
In alkaptonuria, it was found that the defective phenotype of dark urine is due to the inborn error happening during the waste elimination process.
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What contribution did Florence Nightingale make to the medical field?
She opened the first medical
practice for
women.
( <span>it creates <span>July 9, 1860 :</span></span>Nightingale Training School ,<span>The school is now called Florence Nightingale School of <span>Nursing and Midwifery)</span></span>
T . When you refuse to do something its cause you know it is wrong or you dont want to do it to be like everyone else .
Yes it does, when alcohol enters the body, soon after it spreads
