Answer:
Must occur within 12 months of the approval date.
Explanation:
Continuing review of a validated protocol should take place within 12 months of the endorsing date even in the absence or inability to pinpoint further risks.
Review by a convened IRB is not often necessary (take for instance, for a finished study plus data analysis only). Any unexpected problems must be dealt with in the course of the continuing review process, but the review has to entail certain information including the amount of subjects accumulated, any important latest literature, and a sample of the present consent form.
Answer:
Neurotransmitters are chemical substances whose objective is to produce proper communication between neurons. For this to take place, there must be an adequate amount of dopamine and norepinephrine. In children with attention deficit hyperactivity disorder, the production of these two neurotransmitters is irregular; on the other hand, low levels of serotonin are related to the appearance and maintenance of obsessive-compulsive disorder.
Explanation:
Attention deficit hyperactivity disorder is one of the disorders linked to insufficient production of the neurotransmitters dopamine and norepinephrine. This deficit of dopamine and norepinephrine causes problems in the regulatory circuits of various areas of the brain: the prefrontal cortex, the corpus callosum, and the basal ganglia. It is characterized by a difficulty in maintaining voluntary attention in the face of activities; on the other hand, low levels of serotonin are related to the appearance and maintenance of obsessive-compulsive disorder. Serotonin is a neurotransmitter involved in various cognitive processes: modulation of mood, learning, memory, physiological responses, etc. Low levels of serotonin produce unusual responses, overexciting activation in the orbitofrontal cortex, affecting thought and behavior.
Answer:
Older married couples usually have fairly marital satisfaction.
Explanation:
Marital satisfaction is a sense of happiness, satisfaction and stability in marriage. It is an instrument for accessing the success of marriage and it is define by joy the husband and wife experience.
Several factors affect marital satisfaction and this include age of marriage, marriage duration, personality, family, ones perspective and thinking e.t.c.
As couples grow older, there is decrease in marital satisfaction and this is one of the reason why there is divorced among middle aged couples.
This decrease in marital satisfaction can be as a result of child bearing and increased responsibilities of catering for the children. In older age as children leave home, there is increase in marital satisfaction because there is decrease in financial responsibilities.
“First stage” will be the answer you are looking for hope this helps