Well, the Mayan's were quite a secluded, BIG civilization, which did not trade a lot (traded with the Olmec) and was a bit independent. Some differences were the style of their clothing. The Mayans believed deeply that their clothing should have symbols from their gods. Another difference, would be that the Olmec traded a lot more with the North, yet was not as large as the Mayans, but were technologically further advanced as the Mayans used string for their writing. Sorry this is not terse but I hope this little info. helps you.
Answer:
while mesoamerican civilization knew of the wheel and basic metallurgy, the technologies became important. the earliest complex civilization was Olmec culture, which inhabited the gulf of mexico. (known for Olmec, Maya, Zapotec, Teotihuacan, Mixtec, and Mexica (or Aztec)
That Spain was there greatest enemy. Hope this helps <span>(∩ ͡° ͜ʖ</span>