Answer:
Harmful mutations may cause genetic disorders or cancer. A genetic disorder is a disease caused by a mutation in one or a few genes. A human example is cystic fibrosis. A mutation in a single gene causes the body to produce thick, sticky mucus that clogs the lungs and blocks ducts in digestive organs.
Mutations arise spontaneously at low frequency owing to the chemical instability of purine and pyrimidine bases and to errors during DNA replication. Natural exposure of an organism to certain environmental factors, such as ultraviolet light and chemical carcinogens (e.g., aflatoxin B1), also can cause mutations.
only a small percentage of mutations cause genetic disorders—most have no impact on health or development. For example, some mutations alter a gene's DNA sequence but do not change the function of the protein made by the gene.
Answer:
they believe the rulers were not following the Mandate of Heaven
Explanation:
they believe that it was a sign of Heavens disfavor with whomever is currently in charge
It's called vaccine unbundling
it's commonly found in Europe and south Asia. It is very common for vaccines to be sold in a packeted form
Unbundling a vaccine can make you get a specific vaccine that you want at a lower cost