The pathophysiology instructor who is teaching nursing students about chronic pancreatitis should stress upon its complications like <u>pancreatic necrosis,</u> fluid and electrolyte imbalance or disturbances, and septic shock.
Explanation:
The pathophysiology of chronic pancreatitis includes destruction of the fibrous pancreatic secretory parenchyma with intra and extracellular loss, obstruction of ducts and transport of pancreatic secretions, and triggering of enzymatic activities.
These conditions lead to autodigestion and histological destruction of pancreatic tissues leading to necrosis and complete organ damage.
Pancreatic necrosis can result in hemorrhagic or septic shock which can further lead to multiple organ failure. Hence, pancreatic necrosis is a major complication leading to morbidity and mortality among pancreatitis patients.
The structural damages lead to dilatation and malfunctioning of the pancreatic ducts which results in fluid and electrolyte imbalances.
