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Sergeu [11.5K]
3 years ago
14

Briefly explain the steps of cell division in mitosis.

Biology
1 answer:
kifflom [539]3 years ago
4 0
Interphase: growth and development.

Prophase: nucleus begins to disappear and chromosomes are now visible.

Metaphase: the chromosomes align in homologous (the same) pairs in the middle.

Anaphase: The chromosomes begin to move to opposite ends of the cell.

Telophase: The animal cell punches in (creating cleavage) and the plant cell creates a cell plate to help divide the cell.

Cytokines: The cells are completely apart.
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A gene on human chromosome 15 is expressed throughout the body. However, in the brain, only the maternal copy of the gene is exp
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Answer:

C) Through genomic imprinting, methylation regulates expression of the paternal copy of the gene in the brain.

Explanation:

The pattern of gene expression wherein either paternal or maternal gene is expressed in specific cells while the other one is prevented from expression is known as genomic imprinting.

In the given example, the maternal copy of the gene on chromosome 15 is expressed in brain cells while its paternal copy is not expressed in these cells. Hence, the pattern of expression of this gene is regulated through genome imprinting. One of the mechanism is methylation of cytidine residues of CpG islands of the DNA that are more frequently present within promoters of the genes.

When the cytidine residues of these sequences are methylated into 5-methylcytidine, the transcription factors do not bind to these promoters preventing the expression of these genes.

Hence, methylation of cytidine residue in CpG islands of the promoters of the gene present on chromosome 15 could have silenced its expression in brain cells.

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