The probable genotype of the IV-3 with the perspective of autosomal inheritance will be A because he does not have condition A. Therefore both parents must be in condition A.
The probable genotype of IV-3 with the perspective of set=linked inheritance will be BbY this is because he has B condition. Therefore the mothers' genotype must be XBXb and the father's genotype must be XBY.
The probability of IV-4 having condition A is 1/36
Answer:
Why is it important to learn about stem cells and stem cell research?
Researchers hope stem cell studies can help to: Increase understanding of how diseases occur. By watching stem cells mature into cells in bones, heart muscle, nerves, and other organs and tissue, researchers may better understand how diseases and conditions develop.
How does stem cell research affect society?
Research with embryonic stem cells may lead to new, more effective treatments for serious human ailments and alleviate the suffering of thousands of people. Diseases such as juvenile diabetes, Parkinson's disease, heart failure and spinal cord injuries are examples.
The answer is A: a flagship species.
Hope this helps :)
Answer/Explanation:
(1) a mutation in the coding region, resulting in an inactive protein
To check to see if there is a mutation, you could extract the DNA from the cancer cells and then perform PCR to amplify the gene of interest. You could then perform sanger sequencing and compare the sequence to the normal gene to see if a mutation is present. To test the effect of the mutation, you would want to see if an active protein has been formed.
To see if a normal sized protein has been formed, you could perform a western blot, comparing the protein band to the WT protein band. If the protein is absent or much smaller, it is likely not a functional protein.
(2) epigenetic silencing at the promoter of the gene, resulting in reduced transcription.
To check for changes in the epigenetic landscape of the promoter, you could perform chromatin immunoprecipitation by extracting the chromatin from the tumour cells and using antibodies for different chromatin marks to see what has changed between the normal cells and the tumor cells. E.g. H3K9me3, H3K27me3. You would perform a pull down with the antibody of interest and then PCR for your promoter to specifically look at changes at that gene compared to normal cells. To test DNA methylation, you could perform bisulfite sequencing.
To see how transcription is affected, you could extract RNA from the tumor and normal cells, and compare the levels of RNA between the two samples by qRT-PCR
The answer is (C), because, red blood cells or wbc regulate body temperature (Idr), wbc fight infections, and rbc transport nutrients
