I believe the answer id Cnidaria
Answer: Inflammation
Explanation: Inflammation, is caused by the dilation of blood vessels which allows the passage of fluid, antibodies and WBC's into the infected body area
The horrific forced transport of Africans into America during the age of exploration as part of the slave trade that was going on where Africans were transported on ships from Africa, chained up like animals all the way to America was an example of international migration affecting the population.
External influences forced Africans to go from Africa to another continent and live there.