Drugs that have an accepted use in the surgical setting are on the <u>C-II </u>schedule.
Five drug schedules were created and categorised under the Controlled Substance Act in order to regulate their manufacturing and distribution. A requirement of the law states that pharmacists who fill prescriptions for scheduled substances must have a licence from the Drug Enforcement Administration.
The licences of health professionals include special licence numbers that make it possible to trace and associate restricted drug prescriptions with a particular practitioner or distributor.
Drugs in Schedule II are less likely than those in Schedule I to cause use disorders. They are more susceptible to developing physical and mental dependency. They are very susceptible to overuse as well as use disorders. They are frequently used to treat ADHD, sleeplessness, anxiety, and severe pain.
Hydromorphone (Dilaudid®), methadone (Dolophine®), meperidine (Demerol®), oxycodone (OxyContin®, Percocet®), and fentanyl (Sublimaze®, Duragesic®) are a few examples of Schedule II narcotics. Morphine, opium, codeine, and hydrocodone are further Schedule II drugs.
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Answer:
cellular respiration
Explanation:
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Transcription factors are necessary for an initiation of transcription at a regulated gene but not sufficient.
Transcription is the first step of gene expression in which DNA molecule is copied (transcribed) into RNA (mRNA) by RNA polymerase. The process of transcription is divided into three phases:
1. Initiation
• RNA polymerase with transcriptional factors bind to gene promoter Transcription factors can enhance the interaction between RNA polymerase and a DNA sequence- promoter, encouraging the expression of the gene. Such transcription factors are called activators. Otherwise, when the gene expression is inhibited, factors are called repressors and they bind to sequence –operator.
• RNA polymerase unwinds DNA double helix (transcription bubble is formed)
2. Elongation
• RNA polymerases adds nucleotides complementary to DNA
3. Termination
• RNA polymerase gets to stop codon (transcribes a sequence of DNA known as a terminator)
• Formed complementary RNA strand is released from DNA-RNA complex
Enzymes are also known as Biological catalysts. An enzyme working at its maximum possible rate, where the substrate concentration is in excess is <span>V max.
</span><span>The reaction is slow because the molecules are moving slowly and they will not often collide with the active site of an enzyme, so the binding of an enzyme and substrate is rare.</span>
