A reason could be the bodies ability to process the water based vitamin as well as the person's diet. many things have b12 in it but choosing to cut something out, like meat, could cause a deficiency
1. Action potential reaches the axon terminal and depolarizes it.
2. Depolarization opens voltage-gated calcium channels, enabling influx of Ca into the neuron.
3. Calcium binds to specialized proteins on vesicles (containing pre-made acetylcholine) and triggers them to fuse with the neuron membrane at the synapse.
4. Exocytosis of acetylcholine into the synaptic cleft occurs.
5. Acetylcholine diffuses across the synapse and binds to nicotinic receptors on the end plate of the myocyte.
6. Activated nicotinic receptors, themselves ion channels, cause cation influx into the myocyte and generate an end plate potential. This eventually gives rise to the full depolarization within the myocyte that enables contraction.
Trans fat are fats found in thinks like sticks of margarine, snack foods, baked goods, and some fried foods. Trans fats are created when vegetable oils have hydrogen atoms added to them (or hydrogenated). Trans fats can raise cholesterol and increase the risk of heart disease.
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I think the cause would be unprotected sex and well that would also be how its transmitted.
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I don't understand what your trying to say boss, sorry.
