What portion of a pre-mRNA molecule may be cut to be discarded?
ans:- In eukaryote cells the primary transcript (pre-mRNA) is processed. One or more sequences (introns) are cut out.
If the question is referring to an osmosis experiment, the high test concentration of sugar in at the beginning will be INSIDE the visking tubing.
In unicellular organisms, the process of mitosis serves as a method or form of asexual reproduction, as organisms that are unicellular and are typically prokaryotic undergo mitosis to essentially duplicate and make additional offspring that are genetically identical clones as that of the original parent cell. Mitosis in multicellular organisms serves to replace lost, specifically damaged tissue of the organism, it also is crucial for the growth and development of the organism, as it is this particular portion of the cell cycle, when cells after growing and having their DNA duplicated can they separate and produce more and more cells.
Answer:
Thanks for you question. Your hypothesis suggests a linear relationship between serum Cholesterol levels and MI. This hypothesis seems to ignore the difference in the prevalence and effectiveness of LDL receptors in the FH patient.
FH patients who have inherited the mutation from both parents have very few LDL receptors in their blood and therefore almost no ability to pass the unused Cholesterol through the liver. FH patients who are heterozygous will have more LDL receptors although both will find Cholesterol removal problematic without the addition of a PCSK9 inhibitor.
In short, your hypothesis need to account for other factors that are in play.
Explanation:
Consider my case. I am a 64 year old male who has Heterozygous Familial Hypercholesterolemia. Before treatment at age 12 my Total cholesterol was 510 mg/dl. My genetic testing shows two mutations to the LDL Receptor gene with only one mutation being pathogenic. My first heart attack was at 47 and first stroke at 62. My current LDL is too low to detect with the use of a PCSK9 inhibitor (Repatha®).
