Question

A mutation has occurred in the sequence in the promoter region of a bacterial gene, such that the sequence TTGACA has been lost. What process will be most directly affected by this mutation?
RNA polymerase II bindingSplicingTranscription initiationTranslation initiation

Answer 1

Answer: Transcription initiation

Explanation:

In genetics, a promoter is a region of DNA that leads to initiation of transcription of a particular gene. Promoters are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense strand).

Depending on the location and the nature of the genetic defect, ( for example if the sequence TTGACA has been lost), a mutation in the promoter region of a gene may disrupt the normal processes of gene activation by disturbing the ordered recruitment of TRANSCRIPTION FACTORS (TFs) at the promoter.

RNA polymerase || is  just the main transcription enzyme.