The genetic defect most likely causes each leaf to lack a sufficient root system that can support the plant's growth
In catalase chemical reaction of hydrogen peroxide, the enzyme will change hydrogen peroxide into water and oxygen. In this case, hydrogen peroxide will be the substrate. If there is more substrate available, then the chance for the enzyme to bind to the substrate will be higher, thus the reaction speed will be higher in solution with higher hydrogen peroxide
Birth control can prevent that. Such as condoms or diaphragms.