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Ede4ka [16]
3 years ago
15

Classify the following specific inhibitors or inhibitor characteristics according to one of three types of inhibition: reversibl

e competitive, reversible noncompetitev, or irrersible.
A) reversible comp
B) reversible noncomp
C) Irreversible
1. inhibitor binds covalently and permanently at active site.
2. inhibitor strucure resembles substrate structure
3. inhibitor binds noncovalently at site other than active site
4. inhibitor does not alter the max reaction rate
Chemistry
1 answer:
Paraphin [41]3 years ago
5 0

Answer:

A inhibitor structure resembles substrate structure B inhibitor binds non covalently at site other than active site.C  inhibitors bind covalently and permanently at active site.

Explanation:

A Reversible competitive inhibitors structurally resembles the substrate and competes with the substrate to bind to the active site of the target enzyme.

B Reversible noncompetitive inhibitors binds no covalently at site of the target enzyme that is different from the active site.

C irreversible inhibitors interacts very tightly to the active site of an enzyme by covalent bond which cannot be overcome.

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Answer:

              One nucleophilic center

Explanation;

Nucleophile:

                    Nucleophile is a substance which is nucleus loving in nature (<em>Nucleo</em>; Nucleus , <em>phile</em>; Loving). It is known as a specie which donates a lone pair of electrons to electrophile (electron loving) in a chemical reaction.

                    Thus, Nucleophile is the region of higher electron density in a molecule and attacks on the lower electron density region of another molecule. Also, the nucleophile can also contain a negative charge.

Number of Nucleophilic centers in Methanol:

The chemical structure of Methanol is attached below and it can be observed that the oxygen atom is containing two lone pair of electrons. Hence, the oxygen atom can act as a nucleophilic center. Therefore, there is only one nucleophilic center in methanol.

                        H₃C-OH  +  H₃C-Br     →        H₃C-O-CH₃  +  HBr

In above reaction methanol is acting as a nucleophile and is attacking on electrophilic center (Carbon) of methyl bromide yielding dimethyl ether.

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3 years ago
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Chlorine and potassium atoms form ionic bonds, carbon atoms form non-polar covalent bonds with nitrogen atoms, and oxygen forms
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Explanation:

A covalent bond is formed when an element shares its valence electron with another element. This bond is formed between two non metals.

An ionic bond is formed when an element completely transfers its valence electron to another element. The element which donates the electron is known as electropositive element and the element which accepts the electrons is known as electronegative element. This bond is formed between a metal and an non-metal.

Chlorine and potassium atoms form ionic bonds: Ionic bond is formed when there is complete transfer of electron from a highly electropositive metal to a highly electronegative non metal.  Electronegativity difference = electronegativity of chlorine - electronegativity of potassium = 3-0.8 = 2.2

Carbon atoms form non-polar covalent bonds with nitrogen atoms : Non-polar covalent bond is defined as the bond which is formed when there is no difference of electronegativities between the atoms.  Electronegativity difference  = electronegativity of nitrogen  - electronegativity of carbon= 3.0-2.5 = 0.5

Oxygen forms polar covalent bonds with phosphorus: A polar covalent bond is defined as the bond which is formed when there is a difference of electronegativities between the atoms.  Electronegativity difference = electronegativity of oxygen - electronegativity of phosphorous = 3.5- 2.19 = 1.31

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